Also 40 healthy individuals without history of abortion investigated as control group. GTG bonding technique (staining banding with gymsa and trypsin) is used in this study.\n\nResults:
Frequency of chromosomal abnormalities and heteromorphism among couples with three or more abortions were reported respectively 5.3% and 9.3%. This frequency in couples with two abortions Selleckchem BMS-754807 was respectively 3.07% and 6.15%. The frequency of chromosomal heteromorphism in control group was 7.5% and no chromosomal abnormalities were observed in them.\n\nConclusion: This study shows that chromosomal abnormality can be one reason of recurrent spontaneous abortions and more abortion increases the probability of this anomaly. Also, existence of chromosomal heteromorphism in the general population without clinical abortion symptoms shows that chromosomal heteromorphism cannot be the reason Anlotinib concentration of these spontaneous abortions.”
“Environmentally sensitive hydrogels as one of the most potential drug delivery systems have gained considerable interest in recent years. In the present study, we synthesized a newly temperature-responsive composite hydrogel based on attapulgite (ATP) and poly (N-isopropylacrylamide)
(PNIPAM) as the localized drug carriers for drug delivery. The as-prepared ATP/PNIPAM hydrogel has large aperture which significantly improved the quantity of adsorption of drugs, exhibiting the excellent properties of drug release. The scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), and X-ray diffraction (XRD) were used to characterize the ATP/PNIPAM. The swelling/deswelling behaviors and the release of ciprofloxacin lactate were studied. When the temperature was below the low critical solution Selleck GSK2245840 temperature (LCST), the swelling property of hydrogels was excellent and the swelling rate was large. And, the drug release rate increased with the increase of the content of attapulgite in the composite hydrogel
when it was put in the buffer solution (pH 738) at 37.0 degrees C. Therefore, the composite hydrogels might be very useful for its application in biomedical fields. (C) 2014 Elsevier B.V. All rights. reserved.”
“Tanaka K, Terryn S, Geffers L, Garbay S, Pontoglio M, Devuyst O. The transcription factor HNF1 alpha regulates expression of chloride-proton exchanger ClC-5 in the renal proximal tubule. Am J Physiol Renal Physiol 299: F1339-F1347, 2010. First published September 1, 2010; doi:10.1152/ajprenal.00077.2010.-The Cl-/H+ exchanger ClC-5 is essential for the endocytic activity of the proximal tubule cells and the tubular clearance of proteins filtered in the glomeruli.