Correlation analysis showed that destination recall was significantly correlated with episodic recall in HD participants. Destination memory impairment in HD participants seems to be considerably influenced by their episodic memory performance. “
“The ‘beads task’ is used to measure the cognitive basis of delusions, namely the ‘Jumping to Conclusions’ (JTC) reasoning bias. find more However, it is not clear whether the task merely taps executive dysfunction – known to be impaired in patients with schizophrenia – such as planning

and resistance to impulse. To study this, 19 individuals with neurosurgical excisions to the prefrontal cortex, 21 unmedicated adults with Attention Deficit Hyperactivity Disorder (ADHD), and 25 healthy controls completed two conditions of the beads task, in addition to tests of memory and executive function

as well as control tests of probabilistic reasoning ability. The results indicated that the prefrontal lobe group GDC-0973 in vivo (in particular, those with left-sided lesions) demonstrated a JTC bias relative to the ADHD and control groups. Further exploratory analyses indicated that JTC on the beads task was associated with poorer performance in certain executive domains. The results are discussed in terms of the executive demands of the beads task and possible implications for the model of psychotic delusions based on the JTC bias. “
“Three studies are reported on the development of a four-disc version of the Tower of London test of planning ability. The first (n = 138) involved the selection of

items based on rational and empirical criteria to provide a short test of graded difficulty suitable for use with children and clinical populations. The second study (n = 480) checked the properties of the 10-item test Thalidomide on a new sample and in addition examined the internal consistency and factor structure of the test. The third study (n = 61) examined the test–retest reliability of the test over a period of 1 month. The difficulty level of the test remained relatively stable from sample to sample and was sensitive to linear trend in performance from age 5 years up to 30 years. Total score did not reflect the action of a single underlying construct but rather appeared to index a number of factors. Scores were reasonably stable over the 1-month period studied, at least for the children’s sample employed. The four-disc version is a promising method of assessing planning in children and adolescents in clinical situations. “
“Despite a recent upsurge of research, much remains unknown about the neurobiological mechanisms underlying synaesthesia. By integrating results obtained so far in Magnetic Resonance Imaging (MRI) studies, this contribution sheds light on the role of particular brain regions in synaesthetic experiences.