Methods. A user-friendly 10-item questionnaire was specifi cally developed. The scale
included the background date. From a predefi ned scale the patients were subgrouped into 3 categories in relation to SL: (1) “no SL” or “a few days of SL,” (2) “1 week of SL,” and (3)” more than 2 weeks of SL.” The Fisher exact test was used to compare categorical variables. Results. Twenty-three doctors examined 207 Danusertib solubility dmso working patients. A total of 114 patients (56%) completed the follow-up questionnaire. The 10-item scale showed a good correlation between the total score at the fi rst general practitioner visit and predictable time of SL according to the 3 periods. The frequency of BR and referral to radiographical examination was low, and perhaps this was a consequence of using the scale. Conclusion. The specially developed short and user-friendly 10 item LBP scale was a good predictor of the duration of SL. A low rate of BR and radiographical examination may even be the result of using the scale.”
“Background: Preventing recurrence of depression forms an important challenge for current treatments. Cognitive control impairments often remain present during remission of depression, putting remitted depressed patients at heightened risk for new depressive episodes by disrupting emotion regulation
processes. Importantly, research indicates that cognitive control training targeting working memory functioning shows potential in reducing maladaptive emotion regulation and depressive symptomatology in clinically HTS assay depressed patients and at-risk student samples. The current study aims to test the effectiveness of cognitive control training as a preventive intervention in a remitted depressed sample, exploring effects of cognitive control training on rumination and depressive symptomatology, along with indicators of adaptive emotion regulation and functioning. Methods/design: We present a double
blind randomized controlled design. Remitted depressed adults will Selleckchem Staurosporine complete 10 online sessions of a cognitive control training targeting working memory functioning or a low cognitive load training (active control condition) over a period of 14 days. Effects of training on primary outcome measures of rumination and depressive symptomatology will be assessed pre-post training and at three months follow-up, along with secondary outcome measure adaptive emotion regulation. Long-term effects of cognitive control training on broader indicators of functioning will be assessed at three months follow-up (secondary outcome measures). Discussion: This study will provide information about the effectiveness of cognitive control training for remitted depressed adults in reducing vulnerability for depression.