Sonographic biometry in the early second trimester should therefore be utilized to establish perinatal risk, thus allowing prenatal care to be improved.”
“Objective: To define the burden of hand radiological damage in systemic sclerosis (SSc) patients, compared check details with a control group.
Methods: Both hands
of 167 SSc patients and 168 hands (82 right and 86 left) of age- and gender-matched controls were imaged by conventional radiograph. Two musculoskeletal radiologists semiquantitatively scored the following lesions: tuft acro-osteolysis, tuft calcinosis, joint space narrowings, marginal erosions, surface erosions, collapse arthropathies, periarticular calcifications, and juxta-articular osteoporosis, at the following areas: tufts, distal interphalangeal, proximal interphalangeal, metacarpophalangeal, carpal, and first carpometacarpal joints. Clinical and functional characteristics of the 167 SSc patients were obtained from the Belgian Systemic Sclerosis Cohort database.
Results: Tuft acro-osteolysis and calcinosis were the most common findings observed in
SSc patients and were almost absent in controls. SSc patients displaying tuft acro-osteolysis/calcinosis suffered from more severe disease. Arthropathies were infrequently detected and mainly consisted of a mixture of osteoarthritis-related changes (joint space narrowing and surface erosions) also observed in controls and of 2 types of rare SSc-associated arthropathies: a rheumatoid arthritis-like pattern, characterized by marginal erosions (n = 7 patients), and a collapse GSK1838705A arthropathy (n = 6 patients), characterized by pressure erosions and joint find more subluxation.
Conclusions: Although a rheumatoid arthritis-like or a collapse arthropathy can be observed in SSc patients, arthropathies are less common than previously reported. (C) 2011 Elsevier Inc. All rights reserved. Semin Arthritis Rheum 40:455-460″
“Nonmelanoma skin cancer (NMSC) of the
ear can result in large defects with significant morbidity.
To determine whether subanatomic location of NMSCs, based on ease of visualization of the ear, correlated with post-Mohs micrographic surgery (MMS) defect size.
A retrospective chart review of 142 post-MMS ear lesions was performed and categorized according to subanatomic location: the helix, antihelix, and tragus (Location 1); retroauricular (Location 2); and conchal bowl, scapha, and triangular fossa (Location 3).
The average defect sizes were 2.50 cm(2) (Location 1), 5.76 cm(2) (Location 2), and 4.03 cm(2) (Location 3). Tumors in Location 1 were significantly smaller than those occurring in Location 2 (P <.001) and Location 3 (P <.01), but a significant difference in size was not seen between Locations 2 and 3 (P=.16). As a control group, we randomly selected 50 NMSC cases from the nose and found the average defect size of nose NMSCs to be 1.58 cm(2).