Two patients presenting aggressive disease (N+ and pT3a) died of tumour progression after 20 and 14 months, respectively, while the other two are alive
after 56 and 36 months of follow-up with no evidence of disease, stable serum creatinine (2.29 and 1.6 mg/dl) and mild metabolic selleck acidosis. Day and night-time urinary continence were satisfactory in all patients. Good functional outcomes have been reported in the 20 cases of ileal orthotopic neobladder with different techniques published so far and the global experience of 24 cases with a median follow-up of 39 months documents a cancer specific survival of 62.5%.”
“We studied highly L1(0)-ordered FePtAg-C nanogranular film as a potential high-density storage medium in thermally assisted magnetic recording (TAR). A 6.4-nm-thick FePtAg-C film with a perpendicular coercivity of 37 kOe and an average grain size of 6.1 +/- 1.8 nm was fabricated on oxidized silicon substrate with a 10 nm MgO interlayer at 450 degrees C. The time-dependence measurement of remnant coercivity showed the energy barrier of E-b = 7.6 eV similar to 300 k(B)T at room temperature, meaning the excellent
thermal stability for long-term data storage. Static tester experiments on this film using a TAR head demonstrate the feasibility of recording at an areal density of similar to 450 Gbits/in.(2). (C) 2011 American Institute of Physics. [doi:10.1063/1.3536794]“
“The only arterial pathway available after liver transplantation is the hepatic artery. Therefore,
CP673451 Protein Tyrosine Kinase inhibitor hepatic artery thrombosis can result in graft loss necessitating re-transplantation. Herein, we present evidence of Angiogenesis inhibitor neovascularization at long-term follow-up in a series of transplant patients with hepatic artery thrombosis. We termed this phenomenon “”neovascularized liver”. Hepatic artery thrombosis was noted in 30/407 cases (7.37%), and occurred early in 13 patients (43.3%) and late (>30 days) in 17 (56.7%) patients. At the time of this study, 11 (36.7%) patients had a neovascularized liver. Those patients with neovascularized liver and normal liver function were closely followed. Of these patients, 10 (91%) showed evidence of neovascularized liver by imaging, and an echo-Doppler arterial signal was recorded in all patients. The mean interval between the diagnosis of hepatic artery thrombosis and neovascularized liver was 4.1 months (range of 3-5.5 months). Liver histology showed an arterial structure in 4 (36.4%) patients. Four factors were associated with development of neovascularized liver: late hepatic artery thrombosis, early hepatic artery stenosis, site of thrombosis, and Roux-en-Y anastomosis. The overall survival rate at 54 months was 90.9%. In conclusion, a late hepatic artery thrombosis may be quite uneventful and should not automatically lead to re-transplantation.