001) was observed in this subgroup of patients. On the contrary, p-selectin did not change in patients undergoing LRP with BAL. Thus, the results we obtained suggest a greater inhibition effect
of propofol, as compared to sevofluorane, on HSP990 solubility dmso platelet aggregation p-selectin mediated. The different effect of propofol and sevofluorane on p-selectin levels observed in our study is in agreement with previous observations reporting that sevofluorane inhibits human platelet aggregation induced by weak antagonists such as adenosine diphosphate, but not by strong agonists like thrombin [41,42]. Propofol, on the contrary, inhibits platelet aggregation mediated by thrombin  that regulates also the expression of p-selectin on platelets. Conclusions The marked and significant increase in pro-coagulant factors check details and consequent reduction
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